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Vine tea extract dihydromyricetin
Product Introduction
Dihydromyricetin (DHM/Ampelopsin) is naturally extracted from the tender leaves of *Ampelopsis grossedentata* (a plant belonging to the Vitaceae family, commonly referred to as Vine Tea or Berry Tea). Our core raw materials are sourced from designated, standardized cultivation bases located in regions such as Zhangjiajie (Hunan), Tongren (Guizhou), and Enshi (Hubei).
We use low-temperature ethanol-water extraction. vacuum drying
and ultrafine pulverization. The final product is a light yellow to off-white powder that is readily soluble in hot water; slight precipitation may occur after prolonged standing.
We can offering
20%, 50%, 90%, 98% DHM (HPLC)
Water-soluble 15% DHM
Product benefits
Liver Protection & Hangover Relief: Dihydromyricetin accelerates the secretion of acetaldehyde dehydrogenase, rapidly breaking down acetaldehyde—a toxic metabolite of alcohol—thereby reducing the risk of alcoholic fatty liver disease and liver fibrosis. It also inhibits the NF-κB inflammatory pathway and aids in repairing alcohol-damaged hepatocytes. As a core ingredient in numerous liver-support and hangover-relief supplements in Western markets, it effectively alleviates post-drinking symptoms such as headaches, fatigue, and nausea.
Potent, Broad-Spectrum Antioxidant & Free Radical Scavenger: Featuring a polyhydroxylated flavonoid structure, it demonstrates superior free radical scavenging capabilities (against DPPH and ABTS) compared to Vitamin C. It chelates heavy metal ions to minimize cellular oxidative damage, inhibits oxidative aging in the skin and internal organs, and activates SIRT (longevity proteins) and the AMPK pathway to combat cellular senescence.
Regulation of Glucose & Lipid Metabolism: It improves insulin sensitivity, lowers fasting blood glucose and HbA1c levels, and inhibits hepatic lipid accumulation. Furthermore, it assists in regulating blood lipids and reducing the risk of atherosclerosis, making it a key ingredient in formulations for weight management and metabolic health supplements.
Natural Anti-Inflammatory & Gut Repair: It inhibits pro-inflammatory factors such as NLRP3 and NF-κB, repairs the intestinal epithelial barrier, and modulates gut microbiota composition. This helps alleviate symptoms of chronic enteritis and intestinal sensitivity. Additionally, it exhibits natural antibacterial activity against Gram-positive bacteria (e.g., *Staphylococcus aureus*), serving as a natural alternative to certain chemical preservatives.
Anti-Aging Skincare: As a natural inhibitor of DNA methylation, it gently downregulates DNMT1, thereby delaying methylation-induced cellular aging in the skin. It promotes skin firmness, reduces wrinkles, soothes redness, and protects against photoaging, making it a premium ingredient for high-end anti-aging skincare products.
Cardiovascular & Neuroprotection: It protects vascular endothelial cells and enhances nitric oxide production, thereby reducing the formation of atherosclerotic plaques. Capable of crossing the blood-brain barrier, it provides antioxidant protection and repair for neurons, mitigating oxidative damage within the nervous system; it is widely utilized in formulations designed for cardiovascular and neurological health support.
Product applications
Dietary Supplements: hangover liver support capsules/gummies, blood sugar management tablets, anti-aging oral powder;
Cosmetics: anti-aging serum, soothing cream, antioxidant toner & sun care;
Functional Food & Beverage: sugar-free herbal drinks, natural food preservatives for bakery & meat;
Pharmaceutical & Lab Research: liver-protecting drug intermediate, high-purity reference standard for university study;
Animal Feed Additive: natural antioxidant & antibacterial feed raw material replacing antibiotics.
Why choose us？
Free Sample Service: Customers may request free samples ranging from 10g to 50g; shipping costs are payable upon delivery.
Customized Production: We offer customization options for purity levels (90%–99.5%), water-soluble modified DHM, microencapsulated DHM, and ultra-fine powders with a particle size (D90) of less than 10μm.
Rapid Stock Dispatch: We maintain year-round stock for 98% of standard product specifications, with orders dispatched within 24 to 48 hours of payment confirmation. For bulk orders exceeding 25kg, we coordinate sea or air freight logistics and handle all necessary import/export customs documentation.
Technical & Formulation Support: Backed by our in-house R&D laboratory, we provide complimentary guidance on formulation techniques, optimization of ingredient compatibility, and expert answers to product application queries. We also assist clients by providing reference materials for new product registration and filing.
After-Sales Quality Assurance: We offer unconditional returns or exchanges for any products that fail quality inspection upon arrival (i.e., do not match the data specified in the Certificate of Analysis/COA). A dedicated, one-on-one Account Manager is assigned to each client to oversee the entire process—from order placement and logistics to after-sales support.
Tiered Pricing Discounts: We offer tiered pricing negotiations for orders exceeding 100kg. For clients with long-term annual framework agreements, we guarantee locked-in pricing for the entire year and prioritize their orders within our production schedule.
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Q: How should I select the appropriate purity level for Dihydromyricetin (DHM)?
A: The 98% purity grade is recommended for health supplement capsules and high-end skincare products; 50% purity is suitable for mid-range daily chemical products and animal feed additives; 20% purity is intended for standard herbal teas and lower-end compound ingredient blends. For scientific research and laboratory experiments, the ultra-high purity 99.5% grade is preferred.
Q: How can I address the poor water solubility of DHM in my product formulations?
A: Our facility offers custom solutions utilizing cyclodextrin encapsulation or phospholipid complex modification to enhance DHM's water solubility. This process increases solubility by over 15-fold, making it highly compatible with liquid oral supplements and beverage formulations. Custom orders start at a minimum quantity of 5 kg.
Q: Is it possible to customize the powder fineness (particle size) of the product?
A: Yes, we can customize the particle size using ultra-fine pulverization techniques—ranging from a standard 80-mesh size to an ultra-fine powder with a D90 of 5μm—to meet the specific requirements of softgels and high-end serum formulations.
Q: What are the storage conditions and shelf life of the product?
A: The product should be stored in a tightly sealed container in a cool, dry place, away from direct light (ideally below 25°C). The standard shelf life is 24 months.
Q: Can you assist with customs clearance documentation and commercial inspection certificates?
A: Yes, for export orders, we provide the Certificate of Origin (CO), commercial inspection certificates, and factory qualification documents free of charge. We also provide assistance, as needed, with the import registration and filing requirements specific to the customer's destination country.
Q: What is the Minimum Order Quantity (MOQ), and how long does the sample/order processing take?
A: Sample orders (10–50g) are shipped within 1–3 days. For bulk orders, in-stock quantities starting from 1 kg are shipped the same day; larger stock orders (25 kg and above) are dispatched within 2 business days; and custom-specification orders require 7–15 business days for production.
Q: What is the difference between pure DHM and crude extracts of Vine Tea (Ampelopsis grossedentata)?
A: Crude Vine Tea extracts typically contain a DHM content of around 20% and contain a significant amount of impurities. In contrast, 98% purity DHM undergoes rigorous purification via resin adsorption and molecular distillation, resulting in extremely low impurity levels. This ensures superior efficacy and stability, making it ideal for use in compliant dietary supplements and cosmetic products requiring regulatory registration.
For any questions or assistance regarding dihydromyricetin powder, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
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