+86 13096987266
Pterostilbene bulk powder CAS 537-42-8
Product Introduction
Pterostilbene (trans-3,5-dimethoxy-4'-hydroxystilbene) is a dimethylated derivative of resveratrol and belongs to the stilbenoid/polyphenol class. It appears as a white to off-white crystalline powder.
We support two mature mass-production processes to satisfy differentiated procurement demands:
Natural extraction route: Raw materials are sourced from blueberries in North America. Low-temperature physical extraction avoids molecular thermal degradation, securing high-purity natural trans-pterostilbene.
Synthetic purification route (our mainstream industrial bulk supply): Adopt pharmaceutical-grade raw materials for directional synthesis, matched with proprietary multi-stage molecular distillation and recrystallization purification technology. Strictly control cis-pterostilbene isomer content below 0.15% to solve unstable activity caused by isomer mixing in the industry.
Our factory achieves an annual output of 60 tons, maintaining stable spot inventory year-round to mitigate the risk of raw material shortages for downstream mass production.
Product Strength
Optimized molecular structure: Two methoxy groups replace hydroxyl groups compared with resveratrol, LogP value reaches 3.8, lipophilicity is 3 times higher; 60-day high-temperature accelerated stability test shows activity degradation rate less than 3% under light exposure and 60℃, while resveratrol degrades over 25%, effectively reducing finished product rejection rate.
Low impurity system: Single unknown impurity ≤0.3%, total organic impurities ≤1.0%; residual hazardous solvents (methanol, dichloromethane) ＜100 ppm, meeting strict registration requirements of high-end nutraceuticals and pharmaceutical intermediates.
Wide pH tolerance range: Stable between pH 4.0–8.5 without precipitation; compatible with oil suspensions, emulsions and soft capsule systems without extra modification to cut clients’ R&D costs.
Long metabolic half-life of 7 hours (resveratrol only 14 minutes), delivering sustained efficacy for end consumer products and improving market competitiveness of downstream brands.
product Benefits
Powerful Antioxidation & Anti-Inflammation
Activates the Nrf2 antioxidant pathway; DPPH & ABTS free radical scavenging capacity is 40% higher than resveratrol; inhibits NF-κB inflammatory response to relieve chronic low-grade inflammation.
Acts as natural antioxidant stabilizer for grease systems to retard rancidity of unsaturated oils and extend shelf life of soft capsules and oil-based preparations.
Outstanding Oral Bioavailability
Methylated molecular structure resists rapid decomposition by metabolic enzymes; oral bioavailability is approximately 4 times that of resveratrol. Clients can lower formula dosage to control overall raw material cost while guaranteeing end-product efficacy, supported by published clinical literature verifying its 7-hour plasma half-life.
Cardiovascular & Cognitive Protection
Regulates vascular endothelial health and stabilizes blood lipid levels; alleviates neuronal oxidative damage, widely applied in dietary supplements targeting cognitive support and cardiovascular maintenance.
Anti-Aging & Photoprotection for Cosmetics
Resists UV-induced oxidative damage in skin; inhibits matrix metalloproteinase that degrades collagen to improve photoaging and fine lines; relieves sensitive redness for anti-aging serums, repair creams and sunscreen matching antioxidants.
Excellent Processing Stability for Mass Production
High resistance to temperature, light and acid-base fluctuations; no obvious activity loss during conventional pressing, emulsification and filling procedures. Clients can use existing production lines without special low-temperature light-shielding reconstruction to improve production tolerance.
product application
Dietary Supplement Industry
It's suitable for hard capsules, soft capsules, tablets, compound powder blends; commonly compounded with NMN, PQQ for anti-aging formulations targeting longevity care, cognitive support, cardiovascular health and metabolic management, widely adopted by mainstream health brands in Europe, America and Southeast Asia.
Cosmetics & Personal Care Industry
It is applied in anti-aging serums, repair creams, ampoule essences and sunscreen systems. Its high lipophilicity improves transdermal penetration for anti-photoaging and sensitive skin soothing.
Pharmaceutical Intermediates
99.5% high-purity grade serves as lead compounds for pre-clinical research of anti-inflammatory and metabolic regulation drugs. Fully meets pharmaceutical factory audit standards and supports DMF document docking.
Functional Food & Edible Oil Preservation
Natural antioxidant additive for functional edible oils to replace synthetic preservatives, helping brands upgrade to clean-label formulations.
customer case
North American Nutraceutical Brand (Annual order: 12 tons)
High-end anti-aging soft capsules compounded with NMN using our 99% high-purity pterostilbene. Previous supplier suffered unstable HPLC purity leading to unqualified finished content detection. Our stable batch data and technical engineers customized feeding proportion plans, achieving zero quality disputes within one year with scheduled monthly spot delivery.
European Luxury Skincare Manufacturer (Monthly order: 800kg)
Application: Anti-aging repair essence with customized 200-mesh fine powder. Our technical team optimized oil-phase dissolution schemes to solve agglomeration and precipitation issues; final products passed EU cosmetic safety assessment.
Southeast Asian Functional Food Manufacturer
Procured 98% food-grade pterostilbene as natural antioxidant for edible oil to realize clean-label upgrading and pass local food import registration smoothly.
Why choose us？
Scientific Literature & Safety Certification
Cited authoritative journals: Journal of Agricultural and Food Chemistry (lipophilicity & bioavailability data), Cell Metabolism (in vitro antioxidant comparison test);
Toxicological safety verification: Acute oral LD50＞2000mg/kg, no genotoxicity or skin irritation; approved as FDA GRAS safe ingredient and eligible for dietary supplement addition in EU market;
Full Batch Traceability System
Whole-process traceable QR codes covering raw material incoming inspection, synthesis/purification, finished testing and packaging. Clients can query original production records and test data by batch number.
One-Stop Customized B2B Service for Global Buyers
Particle size customization: 80/120/200/300 mesh screening;
Formula technical guidance: solubility debugging, compatibility stability testing, recommended addition dosage and on-site feeding operation guidance;
Custom modified derivatives: cyclodextrin inclusion pterostilbene for improved water solubility on demand.
Flexible Packaging Options
1kg vacuum aluminum foil bag, 5kg/10kg carton, 25kg iron drum lined with sterile double plastic bags; neutral unbranded packaging and OEM private-label repacking are acceptable.
Sufficient Spot Inventory & Fast Delivery
5+ tons regular spot stock for mainstream grades; delivery within 2–3 working days after payment confirmation. Cooperate with bonded warehouses in Shanghai & Ningbo to realize local warehousing and distribution for Europe and North America to shorten logistics lead time.
Customized Compliance Documents
Tailored English customs clearance documents, import registration file arrangement and coordination for third-party designated re-inspection.
Long-Term Strategic Cooperation
Annual price lock agreement, priority production scheduling during peak seasons, exclusive sales and technical engineer one-on-one lifelong follow-up service.
fAQ
Q: What is the difference between your synthetic pterostilbene and natural extracted version?
A: Synthetic trans-pterostilbene features stable purity, low impurities, cost advantages and large-scale stable supply, the mainstream choice for mass industrial production. Natural extracted pterostilbene fits high-end small-batch clean-label brands. We supply both grades as per your requirements.
Q: Can your pterostilbene meet heavy metal standards for EU and US importation?
A: Every batch undergoes SGS ICP-MS testing fully compliant with USP and EU food regulations. Original test reports are provided for customs clearance and third-party re-inspection.
Q: How to solve the poor water solubility of pterostilbene powder?
A: Two mature solutions: optimize oil-phase solubilization formulas; customized cyclodextrin inclusion-modified pterostilbene to significantly improve water solubility provided by our R&D team.
Q: What is the MOQ for bulk orders? Can mixed specifications be shipped in one container?
A: Sample MOQ is 1kg; bulk industrial MOQ is 25kg. Consolidated shipments with mixed specifications are supported.
Q: What is the production lead time for out-of-stock customized grades?
A: Standard in-stock items ship within 2–3 working days; customized specifications require 7–10 working days for production.
Q: Do you support factory on-site inspection or online video workshop audit?
A: Offline factory visits and real-time online video workshop inspections are available; we provide clean workshop layout drawings and complete production procedure records.
Q: Can you guarantee the content of trans-pterostilbene isomer?
A: HPLC strictly controls cis-pterostilbene ≤0.15%; trans-isomer proportion exceeds 99.8% for 99% grade to avoid low-activity cis-isomer interfering with finished product efficacy.
Q: What is the correct storage method for bulk received pterostilbene powder?
A: Keep tightly sealed, store below 25℃ in cool dry warehouses away from direct sunlight and high humidity; unopened packages remain valid for 24 months.
KH Health is your trusted partner, dedicated to listening to customers, solving every problem, and providing quick responses. For any questions or assistance regarding pterostilbene bulk powder, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
Customers' Feedback
packing and shipping
Inquire Now!
If you have any needs, please feel free to contact me and I will be happy to serve you.