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Nervonic Acid (C241) Powder
Product Introduction
Nervonic Acid (C24:1) Powder, chemically known as cis-15-tetracosenoic acid, is a premium, ultra-long-chain monounsaturated omega-9 fatty acid. Recognized as the "core natural component of brain white matter," it is essential for the synthesis and maintenance of myelin sheaths, ensuring rapid and efficient nerve signal transmission.
Our nervonic acid is extracted and refined from Acer truncatum seed oil, offering a renewable, Non-GMO plant source that supports clean-label and sustainability positioning — an advantage over marine-derived material for brand-conscious markets. Supplied as a white to off-white powder or refined oil, it is standardized to 85%, 90%, or 95% assay by gas chromatography (GC), giving formulators a consistent, documented active basis for cognitive, nerve-support, and developmental nutrition products. KOSHER, HALAL, and vegan-compatible options broaden its fit across global markets.
KH health is available in high-purity grades, including 90%, 95%, and ≥98% (tested via GC/HPLC).
product benefits
1 Myelin Sheath Synthesis and Repair
Nervonic acid (C24:1 n-9) is a direct structural precursor of sphingomyelin, the principal lipid component of the myelin sheath that insulates nerve axons in the central and peripheral nervous systems. It bonds with sphingosine to form nervonoyl-sphingomyelin, which is uniquely enriched in white matter. A study published in Cells (2019) demonstrated that naturally occurring nervonic acid ester directly improves myelin synthesis by human oligodendrocytes — the cells responsible for producing myelin in the CNS PMC.
2 Cognitive Function and Memory Support
Emerging clinical evidence links nervonic acid supplementation to measurable improvements in working memory, reaction time, and focus. A Korean double-blind study (2023) evaluated seniors taking 300–600 mg/day of nervonic acid and reported:
-Working memory scores improved by up to 15% within 8 weeks
-Reaction times shortened by 8–12%
-Subjects reported sharper focus and reduced mental fatigue
These effects are attributed to enhanced myelin integrity, improved nerve signal conduction velocity, and modulation of brain energy metabolism.
3 Anti-Neuroinflammatory Activity
Nervonic acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway, a master regulator of pro-inflammatory cytokine production. MedChemExpress research confirms that nervonic acid (20–60 mg/kg, oral gavage) protects the motor system in Parkinson's disease mouse models, and (5–100 mg/kg) improves colonic inflammation in DSS-induced colitis mice via NF-κB inhibition . This dual mechanism — structural myelin support + inflammatory modulation — positions nervonic acid as a unique ingredient for long-term neurological wellness formulations.
4 Antioxidant and Neuroprotective Effects
Recent research in Frontiers in Pharmacology (2026) demonstrated that nervonic acid confers neuroprotection in a zebrafish model of diabetic neuropathy by promoting myelin repair and metabolic modulation, alongside significant antioxidant activity Frontiers. Nervonic acid incorporation into neural cell membranes stabilizes lipid raft structure and reduces susceptibility to oxidative damage.
5 Skin Barrier Repair and Anti-Aging
Beyond neurology, nervonic acid's lipid-repair properties translate to skincare. As a very-long-chain fatty acid, it supports:
-Skin barrier repair — reinforces the stratum corneum lipid matrix
-Moisture retention — reduces transepidermal water loss
-Anti-aging — promotes skin cell regeneration and resilience
-Anti-inflammatory — may help soothe conditions like eczem
product application
1 Dietary Supplements and Nutraceuticals
- Brain health capsules/tablets — standalone nervonic acid (150–300 mg/day) or stacked with DHA, PS, and lion's mane
- Senior cognitive support formulas— targeting age-related memory decline and mental clarity
- Student/academic focus supplements — supporting learning capacity and concentration
- Nerve recovery complexes — post-stroke rehabilitation support, peripheral neuropathy formulas
- Softgel formulations — oil-soluble nervonic acid in omega-3 fish oil blends
2 Functional Foods and Beverages
- Solid beverages — water-soluble nervonic acid (5%, 10%, 20% grades) in brain-boosting drink powders
- Dairy products— milk powder for middle-aged and elderly consumers
- Confectionery — gummies, chewable tablets, energy bars
- Edible oils — blended functional cooking oils (Acer truncatum seed oil blends)
- Convenience foods — nutritional meal replacement shakes
3 Cosmetics and Personal Care
- Anti-aging serums and creams— 0.1–1.0% nervonic acid in lipid-based formulations
- Barrier repair moisturizers — for sensitive and compromised skin
- Eye care products — targeting fine lines and periorbital skin resilience
- Hair and scalp treatments — supporting follicle cell membrane health
- Lipid-repair cleansers — gentle, non-stripping cleansing formulations
4 Pharmaceutical and Research Applications
- Investigational compounds for adrenoleukodystrophy (ALD) and multiple sclerosis (MS) research
- Cell culture media supplements for oligodendrocyte and Schwann cell studies
- Wound healing formulations— nervonic acid has been shown to initiate both neurogenesis and angiogenesis for comprehensive tissue repair.
Customer Success Stories
North American Brain Health Brand: A leading supplement manufacturer required a high-purity, low-heavy-metal ingredient for their new cognitive support line. We supplied 95% pure plant-derived Nervonic Acid with comprehensive third-party COAs. Post-launch, their product achieved a 30% increase in customer repurchase rates due to superior bioavailability and clean-label status.
Asian Premium Dairy Manufacturer: To upgrade their infant formula with "brain-boosting" claims, we provided a 5% Nervonic Acid extract compliant with Novel Food regulations. By assisting with formulation stability testing and regulatory documentation, we helped them successfully launch their new product, capturing significant high-end market share within 6 months.
why choose us?
Customization & Packaging: Available in sizes ranging from 1kg aluminum foil bags to 25kg fiber drums. We offer OEM/ODM services and custom particle size milling.
Free Samples & Technical Support: Request 10g-50g free testing samples. Our senior application engineers provide formulation guidance, solubility testing, and regulatory consulting.
Global Logistics: With domestic and overseas warehousing partnerships, we support DDP, FOB, and CIF trade terms, ensuring safe cold-chain or ambient temperature delivery worldwide.
Strict Quality Traceability: Every batch is accompanied by a detailed COA, MSDS, TDS, and heavy metal/pesticide residue reports. Full traceability ensures your procurement is completely risk-free.
fAQ
Q1: Is your Nervonic Acid plant-derived or synthetically produced?
A: We primarily offer 100% natural plant-extracted Nervonic Acid (Acer truncatum or Malania oleifera). Plant extraction avoids the ethical and ecological issues of animal sources and provides a natural configuration that is highly bioavailable. High-purity synthetic grades are also available for research purposes.
Q2: What is the solubility of Nervonic Acid Powder, and how should it be formulated?
A: Pure Nervonic Acid is lipophilic (fat-soluble). It is insoluble in water but highly soluble in ethanol, vegetable oils, and organic solvents. For food or supplement formulations, we recommend dissolving it in an oil carrier or utilizing microencapsulation/emulsification technologies to create water-dispersible powders.
Q3: What are the recommended storage conditions and shelf life?
A: The shelf life is 24 months when stored in a sealed container, protected from light, in a dry environment at -20°C. For short-term storage, a cool place (<30°C) is acceptable, but long-term freezing is highly recommended to prevent oxidation.
Q4: What is the recommended dosage of Nervonic Acid in food products?
A: According to Chinese Novel Food regulations, the recommended daily intake of Nervonic Acid should not exceed 300mg. Specific addition levels must be adjusted based on the final product format and target demographic (e.g., infants vs. adults).
Q5: Can you provide small packaging and custom purity for R&D?
A: Absolutely. Beyond standard 90%/95% food-grade powders, we supply ≥99% high-purity research-grade standards (10mg to 500g) and custom derivatives (e.g., PEG-MAL modified Nervonic Acid) for drug delivery and cellular experiments.
KH Health is your trusted partner, dedicated to listening to customers, solving every problem, and providing quick responses. For any questions or assistance regarding nervonic acid (C241) powder, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
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