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Lotus leaf extract powder

CAS:475-83-2

Active Ingredient: Nuciferine 2%–98%

Appearance: Brownish-yellow fine powder to white crystalline powder

Test Method: UV/HPLC

Solubility: Sparingly soluble in water

Storage Conditions: Store in a sealed container, protected from light and moisture

MOQ: 25 kg

     Product Introduction

    Lotus leaf extract powder nuciferine is a natural aporphine alkaloid derived from the dried, mature leaves of *Nelumbo nucifera* Gaertn. (sourced from Hunan, China). Our manufacturing process utilizes enzymatic pretreatment combined with low-temperature ultrasonic extraction within a clean-room environment; we strictly prohibit sulfur fumigation and the artificial addition or blending of synthetic nuciferine.
    Every batch undergoes comprehensive in-house testing and random sampling by authoritative third-party agencies (such as SGS or Intertek) to ensure the product is free from pesticide residues, residual solvents, and GMOs, and is non-irradiated.
    Available specifications include:
    Ratio 10:1
    2%–5% Nuciferine: Brownish-tan fine powder (full-spectrum lotus leaf extract)
    10%–20% Nuciferine: Pale yellow powder
    98% Nuciferine: White, needle-like crystalline powder
    Note: UV-grade product is water-soluble, whereas HPLC-grade product is not water-soluble.

     Product benefits

    Metabolic Regulation & Weight Management: Targets PPARα/γ receptors to enhance insulin sensitivity, accelerate the breakdown of subcutaneous and visceral fat, inhibit adipocyte differentiation and accumulation, and lower serum triglycerides and cholesterol; widely used in fat-loss dietary supplements; lipid-lowering mechanisms validated by multiple studies in *Frontiers in Nutrition* and clinical reviews from Nanjing University of Chinese Medicine.
    Antioxidant & Anti-inflammatory Activity: Scavenges ROS free radicals, inhibits the release of pro-inflammatory cytokines (TNF-α, IL-6), and alleviates oxidative stress damage; research from Hangzhou Medical College published in *Phytomedicine* (IF 6.7) confirms inhibition of inflammatory damage via the PI3K/Akt/NF-κB pathway, protecting liver and kidney cells as well as renal tubules against ferroptosis.
    Neurological Soothing & Sleep Support: Antagonizes 5-HT2A/2C receptors and acts as a partial agonist for D2 dopamine receptors to soothe anxiety and improve sleep onset; offers gentle sedation without dependency, making it suitable for sleep-support dietary products.
    Skin Care, Anti-aging & Melanin Inhibition: Inhibits tyrosinase activity and reduces melanin production; provides antioxidant protection against UV-induced photoaging and improves skin dullness and fine lines; serves as a natural ingredient for anti-aging skincare (data on melanin inhibition in B16 melanoma cells available upon request).
    Liver Protection: Reduces free radical-induced lipid peroxidation in hepatocytes and aids in managing non-alcoholic fatty liver disease (NAFLD); a common ingredient in liver-protective and detoxification formulations.

      Product applications

    Dietary Supplements
    Fat-loss capsules/tablets, satiety-inducing meal replacement powders, sleep-support gummies, liver-protective nutrient complexes, and blood-sugar-regulating supplements; features mainstream Western natural botanical ingredients for weight management, suitable for "Clean Label" formulations.
    Cosmetics & Skincare
    Anti-aging serums, brightening and spot-fading creams, soothing and repairing masks, and oil-control body lotions; highlight natural botanical antioxidant and anti-pigmentation properties; ideal ingredients for organic skincare products.
    Pharmaceutical Intermediates & Research Reagents
    Pharmacological reference standards, APIs for new drug development, and reagents for *in vitro* cell assays (high-purity 98% specifications supplied specifically to pharmaceutical companies).
    Functional Foods
    Solid beverages, compressed candies, and herbal teas.

     Why choose us?

    Free Sample Service: Request free high-purity samples (10g–50g) with freight collect; free shipping available for bulk purchase samples to facilitate formulation testing and third-party inspections.
    Customization (OEM/ODM): Tailored specifications including active ingredient content (3%–99%), water-soluble Nuciferine modification, and particle size (60/100/200 mesh); small-batch packaging options (100g/500g aluminum foil bags) available.
    Technical & Formulation Support: In-house R&D team of plant extract engineers providing free formulation optimization, dosage guidance, and solubility improvement solutions, as well as assistance with product registration documentation.
    Quality Documentation: Each shipment includes a full documentation package (COA, heavy metal report, MSDS, and qualification certificates) to support customs clearance and market registration in Europe and the US.
    Stock & Lead Time: Comprehensive stock maintained; orders under 25kg ship within 7 working days, while container-scale orders are produced and delivered within 10–15 working days. Payment via T/T, L/C, or Western Union accepted; assistance provided for FOB customs declaration at domestic ports.
    After-Sales Guarantee: Unconditional return or exchange if spot checks upon arrival reveal non-compliant content; full batch traceability and a 24-month quality warranty.

     fAQ

    Q1: How should I choose between the 2% Nuciferine extract and the 98% high-purity powder?
    A: For end-product applications like health supplement tablets or solid beverages, the 2%–5% full extract is recommended (offering high cost-performance). For high-concentration softgels, cosmetic serums, scientific research, or pharmaceutical intermediates, the ≥98% high-purity monomer is preferred due to lower dosage requirements and superior formulation stability.
    Q2: Can the product be exported to the US or EU? What about regulatory compliance?
    A: The product complies with US FDA raw material specifications, EU REACH regulations, and EP (European Pharmacopoeia) standards. We hold complete HALAL, KOSHER, and SGS certifications, enabling smooth customs clearance for exports to the US, Europe, and Southeast Asia; we also assist in providing the necessary documentation for export customs declarations.
    Q3: Nuciferine has poor water solubility; can you provide a customized water-soluble version?
    A: Yes, we offer customized 10% water-soluble inclusion-complex Nuciferine. Produced using a cyclodextrin encapsulation process, it is soluble in cold water and suitable for oral liquid or aqueous formulations. The lead time for customization is 7–10 days.
    Q4: What are the storage requirements? What is the shelf life after opening?
    A: Unopened product should be stored at 2–8°C, away from light, with a shelf life of 24 months. Once opened, it should be sealed and refrigerated, and used within 6 months; avoid exposure to high temperatures, intense light, or humidity, which can cause the degradation of active ingredients.
    Q5: Can you arrange re-testing by a designated third-party agency (e.g., SGS or Intertek)?
    A: Yes. We can arrange third-party testing before placing an order; bulk production proceeds only after the product passes inspection. Testing costs can be negotiated.
    Q6: Is the minimum order quantity (MOQ) less than 1 kg?
    A: For the 98% high-purity research-grade product, the minimum order is a 10g sample, with a 1 kg minimum for commercial mass production. For the 2%–5% extract, the standard minimum is a full 25 kg drum, though we can accommodate smaller trial orders by splitting the packaging.
    For any questions or assistance regarding natural nuciferine powder, feel free to contact us via:
    WeChat: +86 13096987266
    WhatsApp: +86 18792880979  

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