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Hplc gentian extract powder
Product Introduction
Gentian extract is a highly active botanical extract derived from the dried roots and rhizomes of *Gentiana scabra Bge.*—an authentic, indigenous plant of the Gentianaceae family native to China. Our raw materials are sourced from "semi-wild" cultivated Gentian roots grown at our dedicated cultivation bases in Shaanxi, China; these materials undergo a combined water and alcohol extraction process, followed by concentration, purification, and standardization. The primary active constituent of this extract is Gentianoside. The product presents as a fine powder ranging in color from brownish-yellow to light brown; it is free of clumps and impurities, possesses the characteristic bitter taste and aroma of Gentian, and exhibits excellent solubility in both water and alcohol.
Our product undergoes rigorous HPLC testing to ensure quality control at the source, featuring a batch-to-batch variation in active ingredient content of no more than ±0.2%, low pesticide residue levels, and compliance with heavy metal limits. KH health strictly adhere to ISO 22000, HACCP, and FDA food-grade standards; our product meets the heavy metal, microbiological, and pesticide residue requirements set forth by both the European and U.S. Pharmacopoeias. A Certificate of Analysis (COA) is provided with every batch, and authoritative third-party testing services (such as SGS) are available upon request.
Product benefits
Liver Protection and Repair: Activates the Keap1-Nrf2 antioxidant pathway, inhibits NF-κB inflammatory signaling, mitigates alcohol- and chemically induced liver damage, reduces the risk of liver fibrosis, and promotes hepatocyte regeneration; stimulates bile secretion (cholagogic effect) and improves lipid metabolism.
Digestive Support and Gastrointestinal Health: Activates oral and gastrointestinal bitter receptors to promote the secretion of saliva, gastric acid, and digestive enzymes; enhances appetite and alleviates bloating, belching, and functional dyspepsia; regulates intestinal microbiota balance and improves nutrient absorption.
Anti-inflammatory, Analgesic, and Antioxidant Effects: Inhibits the release of pro-inflammatory cytokines (TNF-α, IL-6) to relieve symptoms associated with arthritis, muscle soreness, and chronic inflammation; scavenges free radicals, provides antioxidant protection, delays cellular aging, and reinforces the skin barrier.
Metabolic Regulation and Weight Management Support: Activates intestinal bitter receptors to promote fat oxidation, increase energy expenditure, and inhibit fat accumulation; improves insulin sensitivity and regulates blood glucose and lipid balance.
Neuroprotection and Calming Effects: Regulates neurotransmitter balance to alleviate anxiety, improve sleep quality, and protect neurons; offers potential supportive benefits for neurodegenerative diseases (such as Alzheimer's disease).
Product applications
1. Dietary Supplements
Liver Support & Protection: Standardized Gentiopicroside Capsules/Tablets, Milk Thistle + Gentian Liver Support Complex, Alcoholic Liver Injury Repair Formula, Liver & Gallbladder Detox Capsules, Fatty Liver Support Tablets
Digestive Health: Herbal Digestive Bitters & Enzymes, Pre-Meal Appetizer Tincture (Bitters), Functional Dyspepsia Relief Tablets (Slow-Release), Probiotic + Gentian Complex Powder, IBS Relief Formula
Metabolism & Weight Management: Fat Metabolism Activator Powder, Post-Meal Blood Sugar Regulation Tablets, Metabolic Booster Complex Capsules, Appetite Control Herbal Formula, Liver & Gallbladder Support Powder (for Fat Loss)
Anti-Inflammation & Immunity: Chronic Inflammation Relief Formula (Slow-Release), Joint Comfort Herbal Capsules, Immune Modulator Complex Powder, Allergy Relief & Anti-Inflammatory Formula, Post-Surgical Inflammation Repair Tablets
Nervous System & Mood: Anxiety Relief Herbal Tincture, Stress Support Complex Capsules, Sleep Improvement Formula, Mood Uplifter
2. Functional Foods & Beverages
Liver Support Teas: Herbal Liver Support Tea Bags, Gentian & Turmeric Wellness Tea, Caffeine-Free Liver & Gallbladder Balancing Tea, Late-Night Recovery Tea Bags
Functional Drinks: Low-Sugar Herbal Energy Drink, Digestive & Appetizing Sparkling Water, Probiotic-Fermented Gentian Drink, Post-Meal Digestive & Liver-Protecting Fruit Vinegar Drink, Post-Workout Metabolic Recovery Drink
Instant Beverages (Powders): Instant Liver Support Powder, Pre-Meal Appetizer Powder, Post-Meal Digestive Aid Powder, Herbal Electrolyte Powder, Liver & Gallbladder Detox Meal Replacement Powder:Flavorings & Alcoholic Beverages: Natural Bitter Flavoring (for Sugar-Free Drinks/Sauces), Herbal Aperitivo, Bitter Liqueur, Craft Beer Flavor Modifier, Low-Alcohol Herbal Flavored Drink
Baked Goods & Snacks: Bitter Dark Chocolate, Herbal-Flavored Biscuits/Cookies, Sugar-Free Hard Candies (Naturally Bitter), Digestive Health Cereal Bars, Functional Baking Premixes
3. Cosmetics & Personal Care
Facial Care: Anti-inflammatory & Soothing Serum, Redness-Relief Cream, Toner for Sensitive Skin, Acne-Fighting & Oil-Control Serum, Post-Procedure Repair Mask, Antioxidant & Anti-Wrinkle Lotion, Skin-Brightening Essence Water, Skin Barrier Repair Lotion
Body Care: Soothing Body Wash, Anti-inflammatory Body Lotion, Soap for Sensitive Skin, After-Sun Repair Gel, Herbal Body Essence Oil
Scalp & Hair: Scalp Soothing Serum, Oil-Control & Anti-Hair Loss Shampoo, Scalp Care Solution for Sensitive Skin, Conditioner for Permed & Dyed Hair, Gentian & Black Diamond Hair Essence Oil
Oral Care: Herbal Mouthwash, Anti-inflammatory Toothpaste, Oral Spray, Gum Soothing Gel
Natural Preservatives & Raw Materials: Plant-Derived Bitter Preservatives, Antioxidant Stabilizers, Natural Herbal Fragrance Ingredients, Certified Organic Skincare Ingredients
4. Pharmaceutical Intermediates & Health Formulations
Prescription / OTC Drugs: Adjunctive Therapy for Hepato-biliary Disorders, Tablets for Indigestion, Anti-inflammatory Formulations for Chronic Inflammation, Compound Granules for Liver Protection & Bile Promotion, Herbal Tinctures for Digestive Health
Pharmacopoeia-Standard Raw Materials: Gentian Extract (USP/EP Compliant), Gentianopicroside Reference Standards, Pharmaceutical-Grade Intermediates, Standardized Extracts / Fluid Extracts
Homeopathy & Herbal Medicine: Bach Flower Remedies (Gentian), Herbal Bitter Tinctures, Traditional Herbal Compounds, Constitutional Conditioning Formulas
5. Animal Feed & Pet Health
Companion Animals (Dogs & Cats): Liver-Protecting Chewable Tablets, Appetite Stimulants for Picky Eaters, Formulas for Soothing Intestinal Inflammation, Post-Surgical Hepato-biliary Support, Adjunctive Care for Chronic Hepatitis
Livestock & Poultry: Hepato-biliary Protection Additives (Broilers/Layers), Digestive Promoters for Piglets, Liver-Protecting & Bile-Promoting Formulas for Dairy Cattle, Compound Powders for Improving Feed Conversion, Anti-Stress Herbal Additives
Aquaculture: Preventives for Fish & Shrimp Hepato-biliary Syndrome, Digestive Enzyme Promoters, Immune-Boosting Formulas, Ingredients for Mitigating Water Quality Stress
6. Industrial & Daily Chemical Auxiliaries
Natural Antioxidants / Stability: Eco-friendly stabilizers for plastics and rubber; antioxidant additives for skincare products; natural ingredients for food preservation.
Plant Dyes & Textiles: Natural mordanting aids for yellow-green shades; color-fixing agents for cotton, linen, silk, and wool fabrics; eco-friendly plant-based dyeing formulations.
Water Treatment & Metalworking: Eco-friendly chelating agents for water treatment; natural auxiliary components for metal surface corrosion inhibition.
Why choose us？
Academic Research Support: Citing multiple studies published in *Frontiers in Pharmacology* (2025), PubMed (2025), and PMC (2025), we confirm the pharmacological mechanisms of Gentioside, including its hepatoprotective, anti-inflammatory, antioxidant, and metabolic-regulating properties. With an LD50 > 5000 mg/kg, it demonstrates low toxicity and a high safety profile.
Production & Quality Control System: Manufactured in a Class 100,000 cleanroom environment, our entire process—from raw material screening, extraction, and concentration to purification, drying, and packaging—is monitored in real-time via HPLC. Every batch is accompanied by a Certificate of Analysis (COA) and verified through independent third-party testing (SGS) to ensure consistent potency, controlled impurity levels, and full regulatory compliance.
Authoritative Certifications: We hold ISO 9001 (Quality Management), ISO 22000 (Food Safety), HACCP, Halal, and Kosher certifications, as well as FDA food-grade registration. Our products are cleared for direct export to global markets, including Europe, the Americas, and Southeast Asia.
Proven Customer Success: We serve over 50 countries and more than 200 brand clients—spanning the dietary supplement, food & beverage, and cosmetics industries. Our bulk repurchase rate exceeds 90%, with zero quality complaints to date, demonstrating our capability to seamlessly meet OEM/ODM customization requirements.
Ready Stock & Rapid Delivery: We maintain a standing inventory of over 5,000 kg. Minimum order quantities start at 25 kg, with shipments dispatched within 3–5 days. Bulk orders (≥100 kg) are delivered within 7–10 days.
Customized Services & Flexible Solutions: We offer tailored solutions, including Gentioside with purity levels ranging from 3% to 80%, custom compound extract formulations, exclusive packaging designs, and comprehensive OEM/ODM contract manufacturing services to meet the diverse and unique needs of our clients.
Professional Technical Support: We provide complimentary samples (10–20 g), expert guidance on formulation R&D, optimization of application protocols, and market trend analysis. Our dedicated technical team offers 24-hour responsiveness to help resolve critical challenges encountered during R&D and production phases.
Quality Assurance & Worry-Free After-Sales Service: We offer unconditional returns or exchanges for any quality-related issues and provide a full quality guarantee throughout the product's shelf life. Optional cold-chain logistics are available, and we provide all necessary customs clearance documentation and Certificates of Origin to facilitate smooth global trade operations.
Price Advantage & High Cost-Effectiveness: Direct supply from the source factory—no markups from intermediaries.
fAQ
Q: What is the difference between 3% Gentian Extract and High-Purity (80%) Gentiopicroside?
A: The 3% product is a standardized natural extract that retains the synergistic active components found in Gentian—including gentiopicroside, swertiamarin, flavonoids, and polysaccharides. It offers more comprehensive efficacy, provides better value for money, and is suitable for general health supplements and food products. The 80% product is a single-component isolate; it features high purity and a higher price point, making it ideal for high-end pharmaceuticals and precision formulations.
Q: Does the product comply with EU/US food standards?
A: Absolutely. It holds ISO, HACCP, HALAL, and KOSHER certifications, as well as FDA food-grade registration. Levels of heavy metals, microbial contaminants, and pesticide residues are all below the limits set by the EU and US Pharmacopoeias. Each batch is accompanied by a Certificate of Analysis (COA) and a third-party testing report.
Q: Are samples free? How long does delivery take?
A: We provide free samples (10–20g); you only need to cover the shipping costs. Delivery takes 3–5 days domestically and 7–10 days internationally. The quality of the samples is identical to that of the bulk shipment.
Q: What is the product's shelf life? How should it be stored?
A: The shelf life is 24 months when unopened. It should be stored in a sealed container, away from light, in a cool and dry place (temperature ≤ 25°C, humidity ≤ 60%). Once opened, it is recommended to use the product within 3 months.
Q: Do you support OEM/ODM customization? What is the Minimum Order Quantity (MOQ)?
A: We support full-process OEM/ODM services (covering formulation design, production, packaging, and private labeling).
Q: What is the primary source of the bitterness in Gentian Extract? Does it affect its application?
A: The bitterness primarily stems from Gentiopicroside and Swertiamarin—natural attributes of these active ingredients. The issue of bitterness can be resolved through **formulation optimization (e.g., adding sweeteners or flavor-masking agents)** without compromising the product's efficacy.
For any questions or assistance regarding gentian extract powder, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
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