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Feverfew leaf extract parthenolide

Raw Material Source: Tanacetum parthenium

Active Ingredient: Parthenolide (0.8% customizable)

Chemical formula: C₁₅H₂₀O₃

molecular weight: 248.32 g/mol

Appearance:Brown fine powder

Mesh Size: 100% pass 80 mesh

Solubility: Sparingly soluble in water, soluble in ethanol

     Product Introduction

    Our feverfew leaf extract parthenolide is obtained from low-temperature ethanol extraction, CO₂ supercritical fractionation, and high-purity purification technology. Different from ordinary whole-plant extracts, our product strictly uses fresh mature feverfew leaves (no stems, no impurities) as raw materials, which effectively avoids the problem of low parthenolide content in stems and ensures the product quality.
    Our independent optimized purification process makes parthenolide account for more than 85% of total sesquiterpene lactones, far exceeding the industry average, with precise content control, stable chemical properties and strong anti-oxidation and anti-interference ability in formula application . The product is brown fine powder, with uniform texture, good solubility in ethanol and organic solvents, moderate lipophilicity, easy formula compatibility and industrial processing.

     Product strength

    Stable active content
    Adopts staged purification technology, parthenolide content error is controlled within ±0.05%, batch consistency is extremely high, avoiding formula efficacy fluctuation caused by unstable raw material content, reducing industrial production adjustment cost.
    Formula compatibility
    Moderate lipophilic and hydrophilic balance, good compatibility with powder, liquid, lipid, and other formula systems, no precipitation, no stratification, strong adaptability to various industrial production processes.
    High anti-oxidation stability
    Effectively resist thermal oxidation and photodegradation, maintain complete molecular structure of parthenolide in high-temperature production and long-term product storage, and ensure long-term efficacy stability of terminal products.
    High safety and low impurity
    Strict industrial purification removes plant fiber, macromolecular impurities and harmful residues, low microbial load, no irritant components, fully compliant with global food, medicine and cosmetic production standards.

     product benefits

    Professional migraine prevention: Parthenolide inhibits NF-κB signaling pathway, reduces platelet aggregation and neurogenic inflammation, clinical trials prove it can reduce migraine attack frequency by 20%-50%, relieve migraine accompanied nausea and vomiting, suitable for long-term preventive health care products development.
    Efficient anti-inflammatory & analgesic: It Inhibit the release of inflammatory factors TNF-α, IL-1β and COX-2, effectively relieve inflammatory pain caused by arthritis, dysmenorrhea and soft tissue inflammation, with mild and lasting efficacy.
    Powerful antioxidant activity: It's rich in apigenin, luteolin and other flavonoids, synergize with parthenolide to scavenge free radicals, reduce oxidative stress damage, and support skin anti-aging and body immune regulation.
    Preclinical anti-tumor potential: In vitro studies confirm that parthenolide can induce tumor cell cycle arrest and apoptosis, inhibit tumor cell proliferation, providing raw material support for pharmaceutical anti-tumor R&D and experimental research.

     product Applications 

    Nutraceutical & Dietary Supplement Industry
    It is used in migraine prevention capsules, anti-inflammatory health tablets, immune regulation powders, and daily health supplements. 
    High-End Cosmetic & Skincare Industry
    It is applied in soothing repair essences, anti-inflammatory skin care creams, redness-relieving lotions, and anti-aging products. Its natural anti-inflammatory and antioxidant properties can effectively soothe sensitive skin, reduce skin inflammation and redness, inhibit skin oxidative aging, mild formula, no irritation, suitable for sensitive skin care product development.
    Pharmaceutical Intermediate & R&D Industry
    As a key natural pharmaceutical intermediate, used in the R&D and experimental production of anti-inflammatory drugs, neurological regulation drugs, and anti-tumor preclinical drugs. High-purity specifications (1.5%, 3%) support laboratory precision experiments and new drug formula iteration.
    Functional Health Food Industry
    It is used in functional herbal teas, anti-inflammatory functional beverages, and daily conditioning health foods to assist in regulating body inflammation, improving digestive discomfort, and relieving tension headaches.

     our service

    Customized Specification Service: We support customized production of different parthenolide content specifications and provide exclusive formula adjustment services according to customer terminal product needs.
    Free Sample Support: We provide 10- 50 g free industrial-grade samples, support customer formula testing and efficacy verification, with sample test reports attached.
    Full-Cycle Quality Traceability: Each batch of products provides complete COA, HPLC, heavy metal and microbial test reports, full production process traceable, compliant with global import and export inspection standards.
    Stable Bulk Supply: Annual output of 50 tons of feverfew leaf extract, sufficient raw material inventory, support long-term bulk order customization, fast delivery (7-10 working days for bulk orders).
    Professional Technical Support: We provide 24-hour professional formula guidance, industrial production process optimization and product efficacy technical consultation services, solve customer formula adaptation problems.
    Global Logistics & After-Sales: We support DDP/FOB/CIF global trade terms, professional export packaging (moisture-proof, high-temperature resistant), perfect after-sales quality assurance system.

     FAQ

    Q1: What is the core advantage of your feverfew leaf extract compared with other suppliers?
    We strictly use pure feverfew leaves as raw materials (no stems and impurities), adopt supercritical CO₂ low-temperature purification technology.
    Q2: What specifications of parthenolide extract can you provide?
    We support full-spec customized production: conventional industrial specifications 0.2%, 0.6% (health food grade).
    Q3: Are your products compliant with global safety standards?
    Yes. All products pass EU Pharmacopoeia and US FDA safety testing; heavy metal, pesticide residue, and solvent residue indicators are far lower than international limit standards, with ISO22000, HALAL, and KOSHER certifications, supporting global market sales and customs clearance.
    Q4: What is the storage method and shelf life of the product?
    The product needs to be stored in a sealed, dry, cool environment (15-25℃), avoiding direct sunlight and high temperatures. The shelf life is 24 months under standard storage conditions, and the active parthenolide content remains stable without significant attenuation.
    Q5: Can you provide customized industrial formulas?
    Yes. Our professional R&D team can provide exclusive formula optimization, dosage adjustment, and process improvement services according to customers' terminal product types, production equipment, and market positioning, helping customers launch products quickly.
    Q6: What is the MOQ and delivery time?
    The minimum order quantity is 25kg bulk industrial packaging. Conventional specifications have sufficient inventory, and bulk orders can be delivered within 3-10 working days.
    For any questions or assistance regarding  parthenolide powder, feel free to contact us via:
    WeChat: +86 13096987266
    WhatsApp: +86 18792880979 

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