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Diindolylmethane dim bulk powder

Product Name:3,3'-Diindolylmethane (DIM) 

CAS Number:1968-05-4    

Molecular Formula:C17H14N2    

Appearance:White to Off-white Crystalline Powder

Purity (HPLC):≥ 98.0%  HPLC

Loss on Drying:≤ 0.5%

     Product Introduction

    KH Health’s 3,3'-Diindolylmethane (DIM) is a premium crystalline compound naturally derived from the enzymatic hydrolysis of Indole-3-Carbinol (I3C), which is abundant in Brassica vegetables such as broccoli, cabbage, and kale. As a specialized natural ingredients manufacturer based in Shaanxi, we utilize advanced extraction and purification technologies to ensure ≥98% purity.
    Our production process strictly controls the dimerization of I3C under acidic conditions to yield a highly pure, stable end-product. We provide comprehensive quality control, including heavy metal testing and solvent residue analysis, ensuring our DIM meets the rigorous standards required for dietary supplements and pharmaceutical intermediates.
    This product is one of our factory's flagship offerings. In addition to natural extracts, we also supply a selection of high-quality chemical products. Supported by a professional R&D team and our own in-house testing laboratory, we maintain a monthly production capacity of approximately one ton, thereby guaranteeing consistent product quality.

      Product benefits

    Estrogen Metabolism Support: DIM acts as a potent modulator of estrogen metabolism. It promotes the beneficial 2-hydroxylation pathway via the activation of the Aryl Hydrocarbon Receptor (AhR), helping to maintain a healthy hormonal balance.
    Androgen Receptor Modulation: Research indicates that DIM functions as a selective androgen receptor modulator, potentially supporting healthy testosterone levels by inhibiting the aromatase enzyme.
    Antioxidant & Anti-inflammatory: Exhibits significant antioxidant properties and helps reduce inflammatory markers by modulating NF-κB signaling pathways.
    Emerging Oral Health Applications: Recent studies (e.g., Baruch et al., 2023) suggest DIM's potential in disrupting Streptococcus mutans biofilms, offering innovative possibilities for oral care formulations.

      product application 

    1. Dietary Supplements: Hormonal Health & Wellness
    1.1 Estrogen Metabolism Support: For women’s health (menopause, PMS) focus on promoting the beneficial 2-hydroxylation pathway of estrogen metabolism.
    1.2 Men’s Vitality & Prostate Health: Used in complex formulas to support healthy testosterone levels by inhibiting aromatase activity and supporting prostate function.
    Since standard DIM has low bioavailability, we offer micronized DIM and lipid-based delivery systems to ensure optimal absorption in capsule and tablet forms.
    2. Pharmaceutical Intermediates: R&D and API Synthesis
    Pharmaceutical researchers value DIM for its specific biological activities.
    2.1 Anti-Tumor Research: DIM is used to develop agents that induce apoptosis in cancer cells. This includes breast, prostate, and colon cancer.
    We provide pharmaceutical-grade DIM with ultra-high purity (≥99%) and comprehensive impurity profiling to support rigorous clinical trials and drug development.
    3. Functional Foods & Beverages: The "Food as Medicine" Trend
    As the functional food market grows, DIM is being incorporated into daily consumption products.
    3.1 Detoxification Tonics: Fortified beverages aimed at liver support and metabolic cleansing.
    3.2 Hormone-Balancing Nutrition Bars: Protein bars enriched with DIM for fitness enthusiasts focusing on hormonal optimization.
    For water-based beverages, we offer Water-Soluble DIM Powder, which solves the solubility issue of crystalline DIM, ensuring clarity and stability in liquid formulations.
    4. Cosmetics & Personal Care: Bio-Active Skincare
    A rapidly growing sector leveraging DIM's antioxidant and anti-biofilm properties.
    4.1 Acne-Fighting Formulations: Based on recent research regarding DIM's ability to disrupt bacterial biofilms, it is increasingly used in topical treatments for acne-prone skin.
    4.2 Anti-Aging Serums: Utilized for their potent antioxidant capacity to neutralize free radicals and protect skin cells from environmental stressors.
    4.3 Scalp Care: Incorporated into shampoos and serums to regulate sebum production associated with androgen fluctuations.

     Why choose us?

    Custom Manufacturing: We offer tailored particle size reduction and microencapsulation services to enhance solubility and bioavailability.
    Private Label & OEM: Comprehensive one-stop solutions from formulation design to finished product packaging.
    Regulatory Support: We provide necessary documentation including COA, MSDS, and allergen statements to assist with your local regulatory compliance.
    Fast Sampling: Free samples (freight collect) are available for quality testing within 3 days.

     fAQ

    Q: What is the difference between I3C and DIM?
    A: Indole-3-Carbinol (I3C) is unstable and converts into various compounds in the stomach acid, whereas DIM is a stable dimer formed from I3C. Supplementing directly with DIM ensures a more predictable and consistent biological effect.
    Q: How do you improve the bioavailability of DIM?
    A: Standard DIM has poor water solubility. We offer micronized powders and lipid-based delivery systems (such as phospholipid complexes) to significantly improve absorption rates compared to generic crystalline DIM.
    Q: Can I get a heavy metal report before placing an order?
    A: Absolutely. We prioritize transparency and safety. A detailed COA including heavy metals, pesticide residues, and microbiological data will be provided with every batch.
    Q:Can I get some samples?
    A:Yes, we can supply the free sample, but the shipping cost be paid by our customers.
    Q:How to start orders or make payments?
    A:Proforma invoice will be sent firsty after confirmation of order, enclosed our bank information. Payment by T/T, PayPal ,Western Union,Trade Assurance or Escrow.
    Q:What's your MOQ?
    A:Our MOQ is 25kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
    Q:How about delivery time?
    A: Delivery time: About 3-5 days after payment confirmed.
    Q:Is there a discount?
    A: Different quantities have different discounts.
    For any questions or assistance regarding high-quality diindolylmethane dim powder, feel free to contact us via:
    WeChat: +86 13096987266
    WhatsApp: +86 18792880979  

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