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Dihydroberberine (DHB) Bulk Powder

Appearance: yellow to yellow-brown powder

Purity (Assay by HPLC): ≥99.0%

CAS Number: 497-30-3

Packaging: 25kg/drum

Shelf Life: 24 months when stored properly

Process: Fermentation / Synthesis

     product introduction

    Dihydroberberine (DHB) bulk powder is a highly bioavailable derivative of natural berberine, widely used in premium dietary supplements for metabolic health, liver support, and cardiovascular care. 
    Our dihydroberberine is manufactured from Coptis chinensis (Chinese Goldthread) roots, a traditional herbal material sourced from contracted planting bases in China. All raw materials are traceable, with strict incoming inspection to avoid heavy metal and pesticide 
    Product Specification
    98% Dihydroberberine by HPLC
    99% Dihydroberberine by HPLC
    Custom purity grades (95%–99.5%) are available for R&D and special formulation requirements.

      Third-party report

    Our lab checks each batch of product to make sure it is really good and meets all requirements.
    Before we ship we can also send some samples to another lab for testing.
    You can choose a lab, like Eurofins, SGS, AIE or any other lab you prefer.
    test report

     product benefits

    Dihydroberberine is known in the supplement industry for being absorbed by the body compared to regular berberine hydrochloride.
    Its main benefits include the following:
    1.Enhanced Absorption and Tolerance
    Dihydroberberine is absorbed about 3 to 5 times better than berberine. This reduces stomach discomfort that can happen when taking doses of berberine.
    2.Supports Healthy Blood Sugar and Metabolism
    Dihydroberberine helps keep blood sugar levels healthy. It does this by improving how the body uses insulin and helps with carbohydrate metabolism. This makes it a good addition to supplements for metabolic health.
    3.Liver and Fat Metabolism Support
    Research shows that dihydroberberine helps keep the liver healthy. It also helps keep levels normal. This is why it is often used in formulas that protect the liver and reduce fatty liver.
    4. Cardiovascular Health Support
    It helps keep cholesterol levels balanced. It supports blood vessels. This is good for heart health.
    5. Powerful Antioxidant and Anti-Inflammatory Activity
    It helps get rid of radicals in the body. It reduces stress caused by oxidation and supports inflammation responses.
    6.Gut Health Support
    It helps keep the balance of bacteria in the intestines healthy. It also supports the health of the barrier.

     Product application

    1. Dietary Supplements
    Dihydroberberine (DHB) bulk powder is primarily used in high-end dietary supplements targeting metabolic health. Its advantage lies in its bioavailability, which is 5 times higher than that of regular berberine. Therefore, it can be used in: Metabolic Health and Glycemic Support Capsules
    It primarily targets insulin sensitivity, glucose metabolism, and postprandial blood sugar control.
    2.Weight Management Formula
    Dihydroberberine can assist in fat metabolism, reduce visceral fat, and suppress appetite.
    3. Liver Detoxification and Cardiovascular Complex
    It protects liver cells, improves fatty liver conditions, and maintains healthy cholesterol levels.
    4.Nutrient Premixes
    It is often used in complex nutrient premix formulations to provide comprehensive health support.
    5.Multivitamin and Mineral Supplements
    Often added to high-potency "whole-body health" multivitamins to enhance their efficacy in metabolic regulation and antioxidant effects.
    6.Sports Nutrition and Anti-Aging Combinations
    Support post-exercise recovery, muscle maintenance, and combat oxidative stress.
    7.Powdered Beverages and Meal Replacements
    Added in low doses to powdered drinks and meal replacements to provide sustained metabolic support.
    8.Nutrition Bars (Energy Bars)
    Used in low-carbohydrate, high-protein nutrition bars designed for blood sugar balance.
    9.Academic and Pharmaceutical Research Institutions: Laboratories worldwide widely use DHB to study signaling pathways related to AMPK activation and NF-κB inhibition.
    10.Cosmetic Research and Skincare
    Due to its powerful antioxidant, acne-fighting, and skin barrier-repairing effects, it is used in high-end skincare formulations.

     Why choose us

    Third-Party Laboratory Testing
    Production Qualifications
    Bulk Wholesale Supply
    Customization Services
    Free Samples
    Technical Support
    Complete Documentation
    Logistics & After-Sales
    US warehouse

     fAQ

    Q: What is the difference between dihydroberberine and berberine HCl?
    A: Dihydroberberine is a hydrogenated derivative with much higher bioavailability (3–5x), better stability, and less gastrointestinal irritation. Berberine HCl is cheaper but absorbs poorly and requires higher doses.
    Q: Is dihydroberberine GRAS approved?
    A: Currently, dihydroberberine does not have FDA GRAS status, but it is widely used as a safe dietary supplement raw material in the United States, Europe, Australia, and Asia.
    Q: How should I store dihydroberberine powder?
    A: Store in a sealed, cool, dry place, away from direct sunlight and high temperatures. Unopened product has a 24-month shelf life.
    Q: Can I get a sample before a bulk order?
    A: Yes, we provide free samples for quality verification. You only need to bear the shipping cost.
    Q: What certificates can you provide?
    A: We can provide COA, MSDS, HPLC, ISO 9001, HACCP, Halal, Kosher, and origin certificates.
    Q: What is your production capacity and delivery time?
    A: Monthly production capacity reaches tons. Stock orders ship within 3–5 working days; customized orders take 7–15 days.
    Q: How do you handle damaged goods during logistics?
    A: We have professional warehouse packing services. The packaging is very sturdy, with double-layered, thickened PE bags inside the cardboard drums. Under normal circumstances, damage will not occur. If such a situation does happen, don't worry, we will resend products of the same quality as soon as possible.
    If you are looking for a reliable supplier, we provide high-purity, dihydroberberine (dhb) bulk powder for food manufacturers, supplement brands, and beverage companies. Contact us for more details about specifications, certificates, and pricing.
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