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Customized pqq disodium salt powder
Product Introduction
PQQ stands for Pyrroloquinoline Quinone Disodium Salt (CAS: 122628-50-6). It is a disodium salt of pyrroloquinoline quinone produced through a process involving high-purity chemical synthesis followed by extensive purification. It serves as a leading active ingredient in the food and dietary supplement sectors and exhibits a neutral pH. Its water solubility and stability are superior to those of PQQ free acid. Unless a client specifies otherwise, we assume that any inquiry regarding PQQ refers to the disodium salt form.
This product is typically manufactured via chemical synthesis (derived from the coupling, cyclization,oxidation,hydrolysis,and purification of ethyl 6-amino-5-methoxy-1H-indole-2-carboxylate and dimethyl 2-oxoglutarate). It is free from animal- or plant-derived impurities and is produced in an ISO 22000-certified facility.
The product presents as a crystalline powder ranging in color from reddish-brown to orange-red; it possesses excellent flowability, does not cake, and is odorless.
Product benefits
1. Mitochondrial Activation
Promotes Mitochondrial Biogenesis: Activates the PGC-1α pathway, enhancing mitochondrial function (increased ATP synthesis) within 3 days; alleviates fatigue and boosts energy levels (*Journal of Nutritional Biochemistry*, 2013).
Enhances Energy Metabolism: Improves cellular energy conversion efficiency, supporting athletic endurance, combating fatigue, and promoting metabolic health.
2. Potent Antioxidant & Anti-inflammatory Action
Scavenges Free Radicals: Acts as a redox coenzyme to neutralize Reactive Oxygen Species (ROS), protecting cells and DNA from oxidative damage; supports anti-aging and cardiovascular health.
Reduces Inflammatory Markers: Alleviates chronic inflammation and aids in the management of metabolic syndrome and fatty liver.
3. Cognitive & Neuroprotection
Neuro-repair: Promotes the production of Nerve Growth Factor (NGF), protects neurons, improves memory, and helps prevent cognitive decline.
Supports Cerebral Blood Flow: Enhances cerebral microcirculation, boosting focus and cognitive function.
4. Metabolism & Weight Management
Regulates Lipid Metabolism: Inhibits fat synthesis and promotes fat oxidation, reducing visceral and hepatic fat accumulation (Animal Study, 2024).
Enhances Insulin Sensitivity: Aids in blood glucose regulation and helps lower the risk of Type 2 diabetes.
5. Liver & Immune Support
Liver Protection: Reduces serum bilirubin and transaminase levels, aids in repairing liver damage, and maintains optimal liver function.
Immune Enhancement: Activates B and T cells and promotes antibody production, thereby boosting overall immunity.
product application
Customized PQQ Disodium Salt Powder is a premium bioactive ingredient widely used across dietary supplements, functional foods, sports nutrition, skincare and wellness formulations.
1. It is highly popular in nootropic & cognitive health products, supporting memory, mental clarity and brain fog relief for students, office workers and middle-aged groups.
2. In anti-aging and longevity formulas, it boosts mitochondrial biogenesis, works perfectly with CoQ10, NMN and curcumin for cellular rejuvenation and anti-senescence.
3. It is also extensively applied in energy & fatigue relief supplements, sports nutrition drinks, protein powders and post-workout recovery products to enhance stamina and reduce physical exhaustion.
4. Moreover, PQQ Disodium Salt is commonly added to metabolism and liver health formulations for insulin sensitivity improvement and visceral fat management.
5. In high-end anti-aging cosmetics, it acts as a powerful antioxidant to activate skin mitochondria, repair cells and improve skin texture. It is also available for research and pharmaceutical intermediate development.
Why choose us？
1. International Regulatory Certifications
FDA GRAS (2017): Generally Recognized as Safe; approved for use in food and dietary supplements by the U.S. Food and Drug Administration.
EU Novel Foods (2018): Approved as a novel food ingredient.
China Novel Food Ingredients (2022): Approved by the National Health Commission for applications such as beverages.
2.Manufacturing & Quality Control Credentials
Certifications: ISO9001, ISO22000, Halal, and Kosher certified.
Batch Documentation:A Certificate of Analysis (COA), HPLC chromatogram, heavy metal/microbiological analysis report, and MSDS are provided with every batch.
3.Customized Production
Purity Customization: Purity levels ranging from 98% to 99.5% (via HPLC) to meet diverse formulation requirements.
Packaging Customization: Available in 1kg aluminum foil bags, 5kg cartons, or 25kg fiber drums; options include neutral packaging or custom-branded packaging.
Labeling Customization: Support provided for English/multi-language labeling, ingredient lists, and compliance with nutritional claims regulations.
4.Quality & Delivery Assurance
Comprehensive Quality Control:Three separate HPLC tests are conducted throughout the entire process—from raw materials to finished products—to ensure batch-to-batch consistency.
5. Technical Support
Formulation Optimization:Recommendations provided for PQQ-based compound formulations (e.g., combined with CoQ10, B-complex vitamins, curcumin, etc.).
Regulatory Consulting: Interpretation of FDA, EU, and Chinese regulations; assistance with product registration and filing processes.
Documentation Support:Provision of COA, MSDS, TDS, heavy metal analysis reports, and microbiological analysis reports.
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Q: What is the difference between PQQ Disodium Salt and PQQ Free Acid?
A:PQQ Disodium Salt is Highly water-soluble (3g/L), stable, and easily absorbed; ideal for use in food and dietary supplements. PQQ Free Acid is poorly soluble in water and less stable; typically used for scientific research or specialized formulations.
Q: What is the recommended dosage?
A:Dietary Supplements:10–20 mg per day (for adults).
Beverages: ≤ 40 mg/kg (per Chinese standards).
Cosmetics: 0.1%–0.5%.
Q: Do your products comply with international standards?
A: Compliant with FDA GRAS, EU Novel Foods, and Chinese Novel Food Ingredient standards; certified under ISO 9001/22000, Halal, and Kosher; third-party testing reports are available upon request.
Q: Can you provide samples?
A: Due to the high value of the product, we provide paid samples ranging from 10g to 50g. Samples are dispatched within 3 days, and we support customers in conducting independent third-party testing.
Q: What is the shelf life? How should it be stored?
A: 24 months (unopened); store in a cool, dry place (<25°C), in a tightly sealed container away from light, and avoid exposure to moisture and high temperatures.
Q: Which ingredients can PQQ be combined with?
A: We recommend combining it with Coenzyme Q10 (for synergistic mitochondrial protection), B-complex vitamins (for energy metabolism), Curcumin (for anti-inflammatory effects), and Vitamin C (for antioxidant effects)** to enhance its overall efficacy.
Q:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q:How to start orders or make payments?
A:Proforma invoice will be sent firsty after confirmation of order, enclosed our bank information. Payment by T/T, PayPal ,Western Union,Trade Assurance or Escrow.
For any questions or assistance regarding high-quality pqq powder, feel free to contact us via:
For any questions or assistance regarding high-quality pqq powder, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
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