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Cosmetic grade 98% alpha arbutin cas 84380-01-8
product introduction
Alpha-arbutin is a glycosylated hydroquinone derivative in which a glucose molecule is attached to hydroquinone in the alpha position. Because the glycosidic bond is more resistant to skin enzymes than in beta-arbutin, alpha-arbutin delivers steadier tyrosinase inhibition with a cleaner impurity profile — which is why leading brightening formulas specify it.
As an alpha arbutin manufacturer, KH Health produces the active by an enzymatic biosynthetic route rather than plant extraction. This gives us full control over purity, batch consistency and the two parameters cosmetic buyers care about most: alpha arbutin 98% assay by HPLC and free hydroquinone at or below 10 ppm.
We also answer formulation and regulatory questions from our own laboratory and export documentation team — from typical use levels to the dossier files cosmetic brands request when registering finished products.
Why choose US
Isomer-Specific Assay
HPLC assay with reference-standard confirmation that the material is the alpha anomer, plus related-substance profiling including any arbutin analogs.
Safety-Critical Impurities
Free hydroquinone quantified on every lot, alongside heavy metals by ICP-MS and residual solvents by GC against ICH limits.
Full Documentation
CoA, MSDS, allergen statement and flow chart per shipment; retained samples stored two years. Independent third-party testing arranged on request.
For skincare OEMs, private-label houses and cosmetic ingredient distributors, working with a direct alpha arbutin supplier removes broker layers, shortens lead times and keeps alpha arbutin wholesale pricing predictable across annual contracts.
Manufacturing & QC
Enzymatic Synthesis
Glycosylation of hydroquinone using immobilized enzymes produces the alpha-anomer selectively, avoiding the beta-anomer found in plant extracts.
Purification
Reaction broth is refined through resin treatment and controlled crystallization to strip hydroquinone and by-products below specification limits.
Crystallization & Drying
White crystals are washed, dried under vacuum and milled to a consistent, free-flowing powder in a humidity-controlled area.
QC Release
Every lot is assayed for alpha-arbutin content, hydroquinone, heavy metals and microbiology before release with full CoA and retention samples.
product Strength
Targeted melanin pathway — alpha-arbutin competitively inhibits tyrosinase, the rate-limiting enzyme of melanin synthesis, supporting evening of dark spots and post-acne marks.
Alpha-bond stability — resistant to enzymatic hydrolysis on skin, alpha-arbutin stays intact longer than beta-arbutin, a key reason formulators choose the alpha form.
Clean impurity profile — hydroquinone controlled to ≤10 ppm supports safer-use documentation in markets where hydroquinone is restricted.
Formulation flexibility — high cold-water solubility and broad pH tolerance let it slot into serums, essences, gels, creams and masks without emulsifier headaches.
Premium claim support — 99% crystalline alpha arbutin gives finished products a strong technical story for dermatology-adjacent and dermo-cosmetic positioning.
Good tolerance profile — at typical use levels of 0.5–2.0% it is considered well tolerated for daily-use leave-on cosmetics when formulated within recommended pH.
Non-animal, biosynthetic — consistent supply independent of plant harvests, with stable alpha arbutin price per kg for annual planning.
Combinable active — pairs routinely with niacinamide, tranexamic acid and vitamin C derivatives in multi-pathway brightening systems.
product application
As a high-end cosmetic-grade whitening active raw material, 98% alpha arbutin is widely used in various skin brightening and repairing cosmeticproducts
standards):
Facial Whitening Skincare Products: Whitening serums, essenceampoules, brightening toners, whitening creams, facial masks, spot-removing essences. It is the core active ingredient of high-end whiteningskincare lines, improving dull and yellowish facial skin.
Body Brightening Products: Body lotions, body whitening creams,hand and foot brightening creams, whole-body skin care products,improving body skin darkening and uneven tone.
Repair & Post-Sun Care Products: Post-sun repair essences, anti-tanning creams, sensitive skin brightening repair products, relieve UVpigmentation and repair damaged skin.
Special Effect Cosmetics: Acne mark repair products, chloasmalightening products, medical beauty auxiliary repair skin care products,safe and effective for pigmentation problem improvement.
Other Personal Care Products: Mild brightening hand care products,private label customized whitening skincare raw materials, supporting OEM/ODM formula development.
customer case
EU Dermo-Cosmetic Brand
Switched from beta-arbutin to our alpha-arbutin 98% grade for a brightening serum relaunch. Isomer-confirmed CoAs simplified their EU product information file updates and claim substantiation.The product has good water solubility, simple formula deployment, stablefinished product effect, and helps customers reduce production costs and improve product competitiveness.
US Ingredient Distributor
Sources trial drums for formulation labs and full bulk for contract manufacturers. Batch CoAs with hydroquinone values under 10 ppm reduced their incoming-QC retesting rate to near zero. Helping customers occupy the mid-to-high-end whitening raw material market in North America.
fAQ
Q:What is the difference between alpha arbutin and beta arbutin?
A:Alpha-arbutin and beta-arbutin are anomers of glycosylated hydroquinone. Alpha-arbutin (CAS 84380-01-8) is produced biosynthetically, resists enzymatic cleavage on skin, and is generally regarded as more stable and effective for tyrosinase inhibition. Beta-arbutin, traditionally extracted from bearberry plants, can be hydrolyzed more readily. Most premium brightening serums therefore specify alpha-arbutin 98% powder.
Q:What is the hydroquinone content of your alpha arbutin?
A:Our alpha arbutin 98% grade controls free hydroquinone to no more than 10 ppm by HPLC, which is the strictest common commercial specification. Each batch CoA states the measured value. Strict hydroquinone control matters because free hydroquinone is the main impurity of concern for skin-lightening actives and is restricted in many cosmetic markets.
Q:What is your MOQ for alpha arbutin bulk, and do you offer samples?
A:Standard MOQ is 25 kg for alpha arbutin wholesale programs, with trial quantities from 1 kg available. Free 20 to 50 g samples ship with CoA and MSDS within 3 to 5 working days. Production lead time is 10 to 15 days after deposit confirmation, making scheduling straightforward for cosmetic OEM and private-label projects.
Q:What documentation do you provide for cosmetic registration?
A:Each alpha arbutin lot ships with CoA, MSDS, allergen statement and product flow chart. For cosmetic notification or registration in the EU, US, China or ASEAN markets we compile ingredient dossiers from batch data. KH Health supplies alpha arbutin as a cosmetic ingredient; food or beverage use is not recommended.
Q: Is the product safe for sensitive skin and daytime use?
A: The shelf life is 24 months under sealed, cool, dry and dark storage conditions. It is recommended to store at 25°C constant temperature, avoid high temperature and humid environment, and seal it in time after opening to prevent oxidation and moisture absorption.
Q: What are the delivery and payment terms?
A: Spot goods can be delivered within 1-3 working days, bulk orders support customized delivery cycle. We support T/T, Western Union, XTransfer, Alibaba payment and other global mainstream payment methods, and support multiple transportation methods such as sea freight, air freight and international express.
KH Health is your trusted partner, dedicated to listening to customers, solving every problem, and providing quick responses. For any questions or assistance regarding alpha arbutin for skincare, feel free to contact us via:
Email: sales@kh-health.com
WeChat: +86 13096987266
WhatsApp: +86 18792880979
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