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Apigenin 98% Powder

Chemical Formula: C₁₅H₁₀O₅

Molecular Weight: 270.24 g/mol

CAS Number: 520-36-5

Specification: Apigenin 98% (HPLC)

Appearance: Fine, yellow to greenish-yellow powder.

Solubility: poorly soluble in water.

     Product Introduction

    KH Health’s Apigenin 98% powder is one of our factory's flagship products. This natural apigenin is derived from dried chamomile flowers or Shandong celery leaves. Typically, the apigenin content in natural extracts is relatively low, resulting in a brownish-yellow color; however, our high-purity 98% product presents as a pale yellowish-green crystalline powder that is sparingly soluble in water.
    Our product undergoes rigorous testing using various methods—including the Area Normalization Method, External Standard Method, and HPLC analysis—allowing clients to select the verification method that best suits their specific requirements. Naturally, the pricing varies accordingly, increasing incrementally with the sophistication of the testing method chosen.

      Product Benefits 

    Potent Antioxidant (Cellular Level): Scavenges free radicals, inhibits lipid peroxidation, and reduces oxidative stress damage; delays cellular aging and lowers the risk of chronic diseases (PMC, 2025).
    Broad-Spectrum Anti-inflammatory: Inhibits inflammatory factors such as TNF-α and IL-6, alleviating chronic inflammation; suitable as an adjuvant ingredient in formulations for arthritis and inflammatory bowel disease (PMC, 2025).
    Neuroprotection + Calming & Sleep Support: Modulates GABA receptors, reduces anxiety, and improves insomnia; non-habit-forming—a natural alternative to melatonin (Finutra, 2025).
    Cardiovascular Health Support: Improves vascular endothelial function, lowers blood pressure, and inhibits atherosclerosis; regulates blood lipids and protects the myocardium (PMC, 2025).
    Skin Anti-Aging + Brightening + UV Protection: Absorbs UVB radiation, inhibits melanin production, and promotes collagen synthesis; utilized in skincare products for brightening, anti-wrinkle, and sun protection applications (ChemicalBook, 2026).
    Liver Detoxification + Metabolic Support: Enhances the activity of hepatic detoxification enzymes and reduces liver damage; serves as an adjuvant ingredient in liver-support formulations (Finutra, 2025).

      product application 

    1. Dietary Supplements
    Ideal for formula development in sleep support, stress relief, full-body antioxidant, liver care, joint health and prostate conditioning.
    It can be formulated into high-purity single-ingredient capsules, compound nutrition tablets, herbal stress-relief blends, and middle-aged & elderly health formulas. It supports vegetarian, keto-friendly and clean-label custom formulations.
    Derived from natural chamomile and plant sources, Apigenin 98% features stable purity, non-GMO and no unnecessary additives. It can be compounded with L-theanine, magnesium and piperine to enhance efficacy, and can also be processed with liposomal encapsulation to boost bioavailability, fully complying with European and American dietary supplement formulation regulations.
    2. Skin Care Products
    Widely used in brightening, anti-aging, UV protection, sensitive skin soothing, post-procedure repair and scalp care & anti-hair loss product lines.
    Suitable for antioxidant serums, anti-aging creams, sunscreen lotions, soothing facial masks, post-laser repair creams, scalp ampoules and anti-hair loss care formulas.
    Apigenin 98% delivers multiple benefits including anti-inflammation & redness reduction, tyrosinase inhibition, free radical scavenging, skin barrier repair and scalp microecology improvement. With stable physicochemical properties, it blends well with niacinamide, centella asiatica, hyaluronic acid and other mainstream cosmetic raw materials, perfect for high-end functional skincare and professional post-procedure repair product development.
    3. Functional Food & Beverages
    Applicable to herbal sleep-aid tea, antioxidant oral liquid, functional sleep shots, plant-based nutrition protein powder, fermented food additives and functional sparkling drinks.
    As a core active ingredient, high-purity Apigenin 98% highlights natural plant flavonoids, melatonin-free mild sleep support, cellular-level antioxidant and post-exercise anti-inflammation recovery. It is widely adopted in premium plant-based health foods, functional solid beverages and herbal drink formulations.
    4. Pharmaceutical Intermediates & Scientific Research
    High-purity Apigenin 98% serves as a premium raw material for anti-inflammatory, anti-tumor and anti-viral preclinical research, featuring low toxicity and stable molecular structure.
    It is widely used in pharmacological cell experiments, animal model studies, CYP450 target research, quorum sensing, biofilm inhibition, and anti-infection & antibacterial drug preliminary development. It also acts as a professional intermediate for pharmaceutical CDMO companies in Phase I/II preclinical research, meeting the purity and testing standards of research-grade reagents and pharmaceutical raw materials.
    5. Pet Health Products
    Perfect for calming & soothing dogs and cats, noise stress relief, separation anxiety regulation, allergic dermatitis relief, itching repair, and compound formulas for senior pets with joint inflammation and nerve soothing demands.
    Commonly formulated into pet calming chews, skin & immune supplement bites, and joint care complex nutrients. Relying on the natural anti-inflammatory, antihistamine and nerve-soothing properties of Apigenin 98%, it helps develop safe, non-addictive herbal health formulas for pets.

     Why choose us?

    Scientific Literature: There are studies from PMC in 2025 that show our products have anti-inflammatory, antioxidant and neuroprotective effects.
    Quality Certifications: We are fully certified with ISO9001, ISO22000, FSSC22000, Halal and Kosher standards. You can download our certificates if you want to.
    Testing Reports: We provide COAs, HPLC chromatograms, heavy metal reports, microbiological reports, and MSDS; third-party re-testing is supported.
    Production Capacity & Inventory: We can make 10 tons of product every month. We usually have 5 to 8 tons of product to ship right away. We can ship our products within 48 hours.
    Client Case Studies: We have served over 200 brands in than 30 countries around the world. These brands are in the supplements, skincare and functional foods industries. client testimonials (anonymized) are available upon request.
    Customization Services: We support customized purity levels (95%–98%), particle sizes, and blended formula R&D; we produce exclusive specifications tailored to specific client requirements.
    Technical Support: Our professional R&D team provides expertise in formula design, process optimization, and regulatory consulting (EU/US/China).
    Supply Chain Assurance: We ensure a long-term, stable supply of raw materials with transparent pricing, guaranteeing both price stability and on-time delivery.
    Logistics & Packaging: Global door-to-door logistics services available, supporting DDP/DDU terms; our moisture-proof and light-shielding packaging ensures product quality remains stable throughout transit.
    After-Sales Support: 24/7 customer service response; unconditional returns or exchanges for any product quality issues; we provide a 12-month quality guarantee.
    US Warehouse:We have a warehouse in the US with our products in stock all year round. This means we can ship our products to you quickly. Our products, including our extracts are available in the US for fast shipping. 

     fAQ

    Q1: What is the primary source of Apigenin 98%? Is it naturally extracted?
    A: High-purity grades (98%) are generally not derived from natural extraction.
    Q2: Do the heavy metal and microbial levels comply with European and US standards?
    A: Yes, they comply with USP-NF 2021 and EU 2015/1933 standards. A third-party ICP-MS report for heavy metals and a microbial analysis report are provided with every batch, allowing for direct use in the regulatory registration of finished products in Europe and the US.
    Q3: What is the Minimum Order Quantity (MOQ)? Are samples available?
    A: The MOQ is 1 kg. Free samples (10–50 g) are available upon request, with shipping costs payable upon delivery.
    Q4: What are the production capacity and lead times? Is stock currently available?
    A: Our monthly production capacity is 10 tons, and orders are shipped within 48 hours. For large-volume orders (≥500 kg), the lead time is 7–10 days.
    Q5: Do you support customized formulations and specifications?
    A: Yes, we support customized purity levels (ranging from 95% to 98%), customized particle sizes, and the R&D of blended formulations.
    Q6: How is Apigenin 98% applied in skincare products? What is its stability like?
    A: The recommended inclusion level is 0.1%–1%, making it suitable for use in serums, creams, and sunscreen products. It demonstrates excellent stability under conditions of **pH 5–7 and temperatures ≤40°C**. It can be effectively combined with other ingredients such as Niacinamide and Hyaluronic Acid.
    Q7: Do you provide regulatory documentation to support the registration of finished products?
    A: We provide comprehensive documentation—including Certificates of Analysis (COA), HPLC chromatograms, heavy metal reports, microbial reports, MSDS, and Certificates of Origin—to meet the regulatory registration requirements for finished products in regions such as the EU, the US, and China.
    KH Health is your trusted partner, dedicated to listening to customers, solving every problem, and providing quick responses. For any questions or assistance regarding apigenin 98% powder, feel free to contact us via:
    WeChat: +86 13096987266
    WhatsApp: +86 18792880979  

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